This unprecedented conference brings together the global health security and innovation communities to define, communicate, and solve our most critical challenges in preventing, predicting, detecting, and responding to global health security threats. The free virtual event will emphasize the importance of locally driven innovation in emerging ecosystems (LMICs) and will promote equitable access to technologies and resources for ensuring health security in all communities. Together participants will create a road map and a call to action for creating and scaling innovative solutions to global health security challenges.